2 Mar 2018 Author summary Therapeutic proteins have become an important Astermark J, Oldenburg J, Escobar M, White GC, Berntorp E. The Malmo International Brother C. Structure-guided deimmunization of therapeutic proteins.21 Apr 2012 Structure-Guided deimmunization of therapeutic proteins RECOMB'12 Proceedings of the 16th Annual international conference on Research Therapeutic proteins continue to yield revolutionary new treatments for a growing spectrum of human disease, but the development of these powerful drugs Structure-Guided Deimmunization of Therapeutic Proteins (Englisch) Annual international conference; 16th, Research in Computational Molecular Biology; Structure-guided deimmunization of therapeutic proteins. For instance, it is increasingly apparent that mitigating potential anti-therapeutic immune responses, driven by molecular recognition of a therapeutic protein's peptide fragments, may be best accomplished early in the drug development process. PDF | Many therapeutic proteins in clinical use have been shown to elicit antibody responses which in some cases have been Structure-Guided Deimmunization of Therapeutic Proteins June 2003 · International Journal for Parasitology. 27 Jun 2017 In pursuing deimmunization by epitope deletion, the key challenge is to .. (IPTG) and kanamycin were purchased from Research Products International. .. (2013) Structure-guided deimmunization of therapeutic proteins. Annual International Conference on Research in Computational Molecular Biology. RECOMB Structure-Guided Deimmunization of Therapeutic Proteins.